CHEMBL333174


SMILES O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2[nH]c3ccccc3c21
InChIKey SPBXLWNNWOLJEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 417.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.35 6.35 6.35 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.24 7.4 7.56 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.93 8.93 8.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database