CHEMBL3342876


SMILES COc1ccccc1N1CCN(CC2COC3(CCN(C(=O)NC(C)(C)C)CC3)O2)CC1
InChIKey MUMWILQJBILXOV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 446.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.89 6.89 6.89 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.45 7.45 7.45 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.9 7.9 7.9 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database