CHEMBL3344458


SMILES CCCCc1cc2c(s1)C[C@H]1c3cc(O)c(OC)cc3CCN1C2
InChIKey RJSAZDFVYLKJQV-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 7.21 7.21 7.21 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.06 6.06 6.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pIC50 6.22 6.22 6.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 6.07 6.07 6.07 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.04 6.04 6.04 ChEMBL