CHEMBL1180604


SMILES Oc1ccc2c(c1)OC(CN1CCc3ccccc3C1)CC2
InChIKey IWUPLAFLTUWLMF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.49 8.86 9.22 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.3 9.3 9.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.37 8.37 8.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database