CHEMBL3361433


SMILES N=C(N)NCC(=O)NCC1(Cc2cccc3ccccc23)CCN(Cc2ccccc2)CC1
InChIKey RGNAMSRVPXMXMY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 443.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pKi 6.95 6.95 6.95 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pKi 7.52 7.52 7.52 ChEMBL
δ OPRD Human Opioid A pKi 5.58 5.58 5.58 ChEMBL
κ OPRK Human Opioid A pKi 5.83 5.83 5.83 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pEC50 5.58 5.58 5.58 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pEC50 6.19 6.19 6.19 ChEMBL