CHEMBL3403336


SMILES Brc1ccc2c(c1)c1c3n2CCN(Cc2ccccc2)C3CCC1
InChIKey IWUMSIWXCHHAQK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 380.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.91 4.91 4.91 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.89 4.89 4.89 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.6 4.6 4.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.58 4.58 4.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database