HARMALINE


SMILES COc1ccc2c3c([nH]c2c1)C(C)=NCC3
InChIKey RERZNCLIYCABFS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 214.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.26 5.26 5.26 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.03 5.03 5.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 4.5 5.05 5.6 ChEMBL