CHEMBL343466


SMILES c1ccc(-n2ccc(CN3CCN(c4ccccn4)CC3)c2)cc1
InChIKey GPHWCCPBYXWRBX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 318.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Green monkey Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D2 DRD2 Green monkey Dopamine A pKi 7.6 7.6 7.6 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.8 8.8 8.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database