CHEMBL345357


SMILES OCc1ccc2c(CN3CCN(c4ccc(Cl)cc4)CC3)cnn2c1
InChIKey SAPCLYRXCUDCRV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 356.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.85 5.85 5.85 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.7 7.71 7.71 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.58 5.58 5.59 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.55 4.59 4.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database