BREMAZOCINE


SMILES CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc31)C2(C)C
InChIKey ZDXGFIXMPOUDFF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 315.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 10.4 10.4 10.4 ChEMBL
μ OPRM Human Opioid A pKi 8.85 9.19 9.7 PDSP Ki database
δ OPRD Human Opioid A pKi 8.64 8.88 9.05 PDSP Ki database
κ OPRK Human Opioid A pKi 10.1 10.31 10.52 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 10.0 10.0 10.0 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 9.52 9.52 9.52 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Bovine Opioid A pIC50 9.3 9.3 9.3 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 8.92 8.92 8.92 ChEMBL
δ OPRD Human Opioid A pIC50 8.82 8.82 8.82 ChEMBL