CHEMBL353220


SMILES COc1ccc(Br)cc1C1=NCC[C@@H](CN2CCN(c3ccccc3)CC2)N1
InChIKey RVBVZFLMCDGFOZ-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 442.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.04 5.04 5.04 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.46 5.46 5.46 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.72 5.72 5.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.8 4.82 4.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database