CHEMBL3546110


SMILES COc1ccccc1N1CCN(CCCCn2cnc3c2c(=O)n(C)c(=O)n3C)CC1
InChIKey NUIQIPXQXFRDIL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.36 6.36 6.36 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.92 8.92 8.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database