CHEMBL3581252


SMILES COc1cc2c(cc1OCC1CC1)C[C@H]1c3c(cc(OC)c(OC)c3-2)CCN1C
InChIKey RITKXTKLSSVWHN-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 395.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database