CV-3988


SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)(OCC[n+]1ccsc1)[O-])OC
InChIKey NMHKTASGTFXJPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 27
Molecular weight (Da) 592.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 6.16 6.2 6.24 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pIC50 6.8 6.8 6.8 Guide to Pharmacology
PAF PTAFR Guinea pig Platelet-activating factor A pIC50 4.59 4.85 5.11 ChEMBL
PAF PTAFR Human Platelet-activating factor A pIC50 6.22 6.22 6.22 ChEMBL