CHEMBL361274


SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc(-c2ccccc2)c[nH]1
InChIKey SWZLGDBFWBZXTL-ZCYQVOJMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 438.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 6.91 6.91 6.91 ChEMBL
μ OPRM Rat Opioid A pKi 7.26 7.26 7.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pEC50 7.72 7.72 7.72 ChEMBL
δ OPRD Human Opioid A pEC50 7.6 7.66 7.72 ChEMBL
μ OPRM Human Opioid A pEC50 5.61 5.61 5.61 ChEMBL