CHEMBL3616855


SMILES Cc1nnc(S[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@H]23)[nH]1
InChIKey ZBBCOPQWFRZNNR-QIMCWZKGSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 298.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.77 6.77 6.77 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.84 7.09 7.35 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.45 5.45 5.45 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 7.01 7.01 7.01 ChEMBL