CHEMBL3628042


SMILES CN1CCN(c2nc(N)nc(/C=C/c3cccc(Cl)c3)n2)CC1
InChIKey PATVLDHTCBKUPZ-AATRIKPKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 330.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pKi 6.07 6.07 6.07 ChEMBL
H4 HRH4 Human Histamine A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 6.36 6.36 6.36 ChEMBL