CHEMBL3663396


SMILES CCOc1ccc2ccccc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2
InChIKey ABBMJPROVMDPMT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 7.96 7.96 7.96 ChEMBL
OX1 OX1R Human Orexin A pKi 8.0 8.0 8.0 ChEMBL
OX2 OX2R Human Orexin A pKi 7.42 7.42 7.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database