KETONALTREXONE


SMILES O=C1c2ccc(O)c3c2C24CCN(CC5CC5)C1[C@]2(O)CCC(=O)[C@@H]4O3
InChIKey MLHMRULRADVYER-ZUPWUQBJSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 6.99 6.99 6.99 ChEMBL
δ OPRD Human Opioid A pKi 6.55 6.55 6.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database