CHEMBL375170


SMILES O=C1c2c(cc(C3CC3)cc2C(F)(F)F)[C@@H]2CNCCN12
InChIKey SZJSOYXYBMPMRH-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 296.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 5.53 5.53 5.53 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.85 7.85 7.85 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.29 6.29 6.29 ChEMBL