CHEMBL3765874


SMILES COc1ccccc1N1CCN(CCCCCC(=O)n2c3ccccc3c3ccccc32)CC1
InChIKey HMYNWIZJJBBFNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 455.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.07 6.07 6.07 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.89 5.89 5.89 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database