CHEMBL3765875


SMILES O=C(CCCCN1CCN(c2ccccc2O)CC1)n1c2ccccc2c2ccccc21
InChIKey CDTNDXMWHPCPSH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.06 7.07 7.07 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.06 6.06 6.06 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database