CHEMBL376690


SMILES C[C@H]1CN2CCN(Cc3ccccc3)C[C@H]2C[C@@]1(C)c1cccc(O)c1
InChIKey BWHIDELHAOMALD-QTGUNEKASA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.85 6.86 6.86 ChEMBL
κ OPRK Human Opioid A pKi 7.36 7.37 7.37 ChEMBL
μ OPRM Human Opioid A pKi 8.92 8.94 8.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 6.82 6.82 6.82 ChEMBL
κ OPRK Human Opioid A pIC50 8.08 8.08 8.08 ChEMBL
μ OPRM Human Opioid A pIC50 7.96 8.55 9.14 ChEMBL