CHEMBL3775197


SMILES Cn1c(SCCCN2CC3CCN(c4ccccc4C(F)(F)F)C3C2)nnc1-c1cccnc1
InChIKey UFUQIVBOXLXINJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 488.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.66 5.66 5.66 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.3 7.9 8.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.9 6.13 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database