CHEMBL3775226


SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(c4ccc(C(F)(F)F)cc4F)C3C2)n1C
InChIKey YTXILLIRPDSLHZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 510.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.61 6.61 6.61 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.96 6.96 6.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.3 8.68 8.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.8 6.83 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database