CHEMBL380330


SMILES COc1ccc2c(c1)CCN(C)CCc1ccccc1C2
InChIKey ATCJEKKXEJVYOB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 281.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.27 7.53 8.14 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.54 7.58 7.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.12 7.12 7.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.89 8.16 9.26 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKd 8.69 8.69 8.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database