CHEMBL3818935


SMILES O=C1NCN(c2ccccc2)C12CCN(CCCCc1nc3ccccc3o1)CC2
InChIKey FPLHVKDUVQOWKV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.8 5.81 5.82 ChEMBL
H1 HRH1 Human Histamine A pKi 6.27 6.27 6.27 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.93 6.93 6.93 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.68 7.68 7.68 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.99 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database