CHEMBL3819726


SMILES Fc1ccc2c(c1)CC(CCN1CCc3ccccc3C1)C2
InChIKey RVYPAMKCWJPLSH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.94 5.94 5.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database