CHEMBL384497


SMILES COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(NCCCc5ccc(Cl)cc5)[C@@H](C2)N(CC2CC2)CC[C@]314
InChIKey HEUWZOULKACFBC-ZBBWKFRYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 506.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.11 7.11 7.11 ChEMBL
δ OPRD Human Opioid A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 8.78 8.78 8.78 ChEMBL
κ OPRK Human Opioid A pIC50 8.73 8.73 8.73 ChEMBL
μ OPRM Human Opioid A pIC50 9.92 9.92 9.92 ChEMBL