CHEMBL1199172


SMILES CN1CCc2[nH]c3ccc(S(=O)(=O)Nc4cccc(F)c4)cc3c2C1
InChIKey RTSLGLYHBXLBEJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 359.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.68 8.68 8.68 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.41 7.41 7.41 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.82 7.82 7.82 ChEMBL