CHEMBL388570


SMILES C[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
InChIKey LSLYOANBFKQKPT-DIFFPNOSSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 5
Rotatable bonds 6
Molecular weight (Da) 303.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Rat Adrenoceptors A pKi 4.83 4.83 4.83 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 6.46 7.24 8.4 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKd 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Rat Adrenoceptors A pEC50 7.14 7.14 7.14 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 9.52 9.52 9.52 ChEMBL
β2 ADRB2 Human Adrenoceptors A pIC50 9.85 9.85 9.85 ChEMBL