CHEMBL389665


SMILES Cc1ccccc1C(c1ccccc1C)N1CCC(O)(c2ccccc2)CC1
InChIKey MHYKPRJMOSXVFG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 371.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.4 8.4 8.4 ChEMBL
δ OPRD Human Opioid A pKi 5.24 5.24 5.24 ChEMBL
κ OPRK Human Opioid A pKi 5.77 5.77 5.77 ChEMBL
μ OPRM Human Opioid A pKi 5.67 5.67 5.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 6.94 6.94 6.94 ChEMBL