CHEMBL3897499


SMILES CCCN1CC[C@H]2c3cc4ccc(C(F)(F)F)cc4nc3[C@H](CC)[C@H]3CCC[C@@H]1[C@@H]32
InChIKey LILDBTJYRFAMFE-VCSLONGPSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 416.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.98 5.98 5.98 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.99 5.99 5.99 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.8 5.8 5.8 ChEMBL
κ OPRK Human Opioid A pKi 6.38 6.38 6.38 ChEMBL
μ OPRM Human Opioid A pKi 5.63 5.63 5.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database