CHEMBL3904946


SMILES O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2ccccc2F)cc1
InChIKey ABNHKWJQNLIOML-YILGNFQOSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 396.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.65 5.82 5.99 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 7.19 7.79 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.12 7.61 8.1 ChEMBL
EP3 PE2R3 Human Prostanoid A pEC50 5.33 5.33 5.33 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 8.4 8.96 9.52 ChEMBL