CHEMBL391487


SMILES CNC(=O)Cn1c(=O)n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c2ccccc21
InChIKey OUDYUUVZVNMOPP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 508.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.0 8.57 9.3 ChEMBL
κ OPRK Guinea pig Opioid A pKi 5.32 5.97 6.32 ChEMBL
δ OPRD Human Opioid A pKi 5.34 5.42 5.47 ChEMBL
μ OPRM Human Opioid A pKi 6.35 6.8 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 6.15 7.52 8.4 ChEMBL