CHEMBL394080


SMILES COc1ccccc1N1CCN(CCCCN2C(=O)Cc3ccccc32)CC1
InChIKey VJMHUOSOEAGNQW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.71 6.71 6.71 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.39 6.46 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database