CHEMBL3949856


SMILES CCC#CC[C@H](C)[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1
InChIKey UMYXRXWDPHAKGZ-XLJJWPCRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKi 8.92 8.92 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 6.12 6.12 6.12 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 8.48 8.48 8.48 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 9.14 9.55 9.96 ChEMBL