dynorphin-(1-11)


SMILES None
InChIKey WZHQALIQGVYQGG-QFIUEGLPSA-N
Sequence YGGFLRRIRPK

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.0 8.0 8.0 Guide to Pharmacology
κ OPRK Human Opioid A pKi 9.7 9.7 9.7 Guide to Pharmacology
μ OPRM Human Opioid A pKi 8.8 8.8 8.8 Guide to Pharmacology
δ OPRD Mouse Opioid A pKi 8.09 8.09 8.09 ChEMBL
κ OPRK Guinea pig Opioid A pKi 9.89 9.89 9.89 ChEMBL
μ OPRM Rat Opioid A pKi 8.46 8.52 8.57 ChEMBL
κ OPRK Human Opioid A pKi 9.92 9.92 9.92 ChEMBL
κ OPRK Rat Opioid A pKi 8.96 8.96 8.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 7.54 7.54 7.54 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 10.11 10.11 10.11 ChEMBL
δ OPRD Human Opioid A pIC50 6.55 7.36 8.16 ChEMBL
κ OPRK Human Opioid A pIC50 7.88 8.92 9.96 ChEMBL