CHEMBL3978590


SMILES O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(C(F)(F)F)c2)cc1
InChIKey UZKOHPYLAOHDTN-FSKZSRKQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 446.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.5 5.69 5.88 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 7.05 8.03 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 5.99 6.72 7.46 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 7.8 8.75 9.7 ChEMBL
TP TA2R Human Prostanoid A pEC50 6.66 6.66 6.66 ChEMBL