CHEMBL3991094


SMILES O=C1c2ccccc2CC1CCN1CCc2ccccc2C1
InChIKey YFSPFZNLWSGJJK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 291.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.58 ChEMBL
H1 HRH1 Human Histamine A pKi 7.6 7.61 7.62 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.32 7.32 7.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.59 5.59 5.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database