SPIROINDANYLOXYMORPHONE


SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)C2(Cc4ccccc4C2)C[C@@]3(O)[C@H]1C5
InChIKey YJWDKWRVFJZBCJ-QVJDATKISA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 6.31 6.7 7.26 ChEMBL
μ OPRM Mouse Opioid A pKi 7.85 7.85 7.85 ChEMBL
δ OPRD Mouse Opioid A pKi 7.33 8.09 8.55 ChEMBL
κ OPRK Guinea pig Opioid A pKi 6.23 6.23 6.23 ChEMBL
μ OPRM Rat Opioid A pKi 6.81 7.42 8.41 ChEMBL
δ OPRD Human Opioid A pKi 8.48 8.63 8.85 ChEMBL
μ OPRM Human Opioid A pKi 7.84 7.84 7.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database