CHEMBL404511


SMILES CC1NC(NCC(F)F)=Nc2cccc(Cl)c21
InChIKey JDPGHZDOBUGUDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 259.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.0 8.1 8.2 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKd 7.41 7.41 7.41 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.48 7.48 7.48 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database