CHEMBL4060073


SMILES CC(C)CN1CCC23c4cc(O)ccc4CC1C21CCC2C3[C@@H](CN2C(=O)c2ccccc2)O1
InChIKey TWGYRBSROHRNIC-BTNQZZBKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 458.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 8.35 8.35 8.35 ChEMBL
δ OPRD Mouse Opioid A pKi 9.12 9.12 9.12 ChEMBL
κ OPRK Guinea pig Opioid A pKi 8.2 8.2 8.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 7.01 7.01 7.01 ChEMBL
δ OPRD Human Opioid A pEC50 8.52 8.52 8.52 ChEMBL