CHEMBL4067629


SMILES Oc1ccc2c(c1)C13CCN(CC4CC4)C(C2)C12CCC1C3[C@@H](CN1c1ccccc1)C2
InChIKey QRVIHLRCMHRVCQ-UTLLKELSSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 426.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.9 8.9 8.9 ChEMBL
κ OPRK Human Opioid A pKi 8.61 8.61 8.61 ChEMBL
μ OPRM Human Opioid A pKi 9.02 9.02 9.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.33 8.33 8.33 ChEMBL
κ OPRK Human Opioid A pEC50 8.09 8.09 8.09 ChEMBL
μ OPRM Human Opioid A pEC50 8.0 8.0 8.0 ChEMBL