enprostil


SMILES COC(=O)CCC=C=CC[C@H]1C(=O)C[C@H]([C@@H]1/C=C/[C@H](COc1ccccc1)O)O
InChIKey PTOJVMZPWPAXER-VFJVYMGBSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 7.1 7.45 7.8 Guide to Pharmacology
EP3 PE2R3 Human Prostanoid A pKi 7.92 7.92 7.92 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 7.4 7.4 7.4 Guide to Pharmacology
FP PF2R Human Prostanoid A pKi 7.1 7.1 7.1 Guide to Pharmacology
EP3 PE2R3 Rat Prostanoid A pKi 7.13 7.13 7.13 Guide to Pharmacology
EP1 PE2R1 Rat Prostanoid A pKi 6.7 6.7 6.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pEC50 8.43 8.43 8.43 Guide to Pharmacology