CHEMBL4070288


SMILES CCc1ccc(C(=O)NCC2c3ccccc3CCN2C)cc1
InChIKey RGAQWGCPPCLXIL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 308.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.64 8.64 8.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 6.72 6.72 6.72 ChEMBL
κ OPRK Human Opioid A pIC50 6.31 6.31 6.31 ChEMBL
μ OPRM Human Opioid A pEC50 8.0 8.0 8.0 ChEMBL
μ OPRM Human Opioid A pIC50 5.48 5.48 5.48 ChEMBL