CHEMBL40711


SMILES COc1ccc(Br)cc1CCc1c(F)cccc1C1=NCCN1
InChIKey WCPPZGPJRHLSKP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 376.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Mouse Melanocortin A pKi 6.8 6.8 6.8 ChEMBL
MC4 MC4R Human Melanocortin A pKi 5.52 6.29 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 5.21 6.06 6.99 ChEMBL