CHEMBL4073330


SMILES O=c1ccc2c(N3CCN(CCCCOc4ccn5nccc5c4)CC3)ccc(O)c2o1
InChIKey FSLWZIRTOUAUNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 434.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.4 7.56 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database