CHEMBL407818


SMILES Oc1ccc(N2CCN(Cc3cnn4ccccc34)CC2)cc1
InChIKey GDEQPGACTRNZFK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 308.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 4.61 4.61 4.61 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.0 5.0 5.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.47 5.47 5.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.06 4.63 5.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database