CHEMBL4090064


SMILES Cc1cc(C)cc(C2CCCN2Cc2ccc(Oc3ccc(C(N)=O)cc3F)c(Cl)c2)c1
InChIKey ZSXFIQRCVUEZOS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.72 6.72 6.72 ChEMBL
κ OPRK Human Opioid A pKi 7.8 7.8 7.8 ChEMBL
μ OPRM Human Opioid A pKi 6.66 6.66 6.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 7.8 7.8 7.8 ChEMBL
κ OPRK Human Opioid A pIC50 8.03 8.03 8.03 ChEMBL
μ OPRM Human Opioid A pIC50 6.84 6.84 6.84 ChEMBL